Britain’s public finances are more vulnerable to shocks than other major economies, the Treasury’s fiscal watchdog said, as

REDMOND, Wash.--(BUSINESS WIRE)--Jul 13, 2023--

HasanAbi criticized both Amouranth and xQc, noting a perceived change in their attitudes after signing lucrative deals with Kick

TL;DR: As of August 23, you can get the OMNIA M2+ MagSafe wireless charging station

By David Shepardson WASHINGTON (Reuters) -U.S. government offices in the Washington area closed early on Monday due to approaching thunderstorms

There’s no sign of Morgan Stanley in Arm Ltd.’s draft filing for its initial public offering, a rare

Scientists have developed an artificial intelligence (AI) tool that can classify four subtypes of Parkinson’s disease with up to 95% accuracy. Researchers from the Francis Crick Institute and the UCL Queen Square Institute of Neurology in London “trained” a computer program to recognise the subtypes of the condition using images of stem cells from patients. The team said their work, published in the journal Nature Machine Intelligence, could pave the way for personalised medicine and targeted drug discovery. Sonia Gandhi, assistant research director and group leader of the Neurodegeneration Biology Laboratory at the Crick, said: “We understand many of the processes that are causing Parkinson’s in people’s brains. The hope is that one day this could lead to fundamental changes in how we deliver personalised medicine Sonia Gandhi, Francis Crick Institute “But, while they are alive, we have no way of knowing which mechanism is happening, and therefore can’t give precise treatments. “We don’t currently have treatments which make a huge difference in the progression of Parkinson’s disease. “Using a model of the patient’s own neurons, and combining this with large numbers of images, we generated an algorithm to classify certain subtypes – a powerful approach that could open the door to identifying disease subtypes in life. “Taking this one step further, our platform would allow us to first test drugs in stem cell models, and predict whether a patient’s brain cells would be likely to respond to a drug, before enrolling into clinical trials. “The hope is that one day this could lead to fundamental changes in how we deliver personalised medicine.” Parkinson’s is a condition in which parts of the brain become progressively damaged over many years. Symptoms include involuntary shaking of particular parts of the body, slow movement, and stiff and inflexible muscles. But there is also a wide range of other physical and psychological symptoms such as depression and anxiety, problems sleeping, and memory problems. These vary from person to person due to differences in the underlying mechanisms causing the disease. The researchers said that until now, there was no way to accurately differentiate Parkinson’s subtypes. It means people are given nonspecific diagnoses and do not always have access to targeted treatments, support or care, the team added. For the study, the researchers generated stem cells, which have the ability to develop into specialised cell types in the body, from patients’ own cells. The team then used those cells to chemically create four different subtypes of Parkinson’s: two involving pathways leading to toxic build-up of a protein called alpha-synuclein and two involving pathways associated with dysfunctional mitochondria, the cell’s battery packs. Working with the British technology company Faculty AI, the team developed machine-learning algorithms which were able to accurately predict the Parkinson’s subtype when presented with images it had not seen before. James Evans, a PhD student at the Crick and UCL, and first co-author of the study, said: “Now that we use more advanced image techniques, we generate vast quantities of data, much of which is discarded when we manually select a few features of interest. “Using AI in this study enabled us to evaluate a larger number of cell features, and assess the importance of these features in discerning (the) disease subtype. “Using deep learning, we were able to extract much more information from our images than with conventional image analysis. “We now hope to expand this approach to understand how these cellular mechanisms contribute to other subtypes of Parkinson’s.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Oxford scientists find no evidence to suggest Facebook not good for wellbeing Many adults would struggle to understand video-sharing platforms’ rules – Ofcom Ozzy Osbourne PlayStation tweet which failed to reveal link to Sony banned

As kids and educators settle into a new school year, a little bit of generosity

Google is set to begin deleting millions of Gmail, Drive and Photos accounts next month as part of a major update to the platform. The purge will impact all personal Google accounts that have been left dormant for at least two years, with emails, documents, spreadsheets, calendar appointments, photos and videos all permanently deleted. The policy was introduced earlier this year but is set to come into effect in December 2023. “We are updating our inactivity policy for Google Accounts to two years across our products,” Ruth Kricheli, Google’s vice president of product management, wrote in a blog post in May. “This update aligns our policy with industry standards around retention and account deletion and also limits the amount of time Google retains your unused personal information.” The move is aimed at protecting active Google users from security threats like phishing scams and account hijacking. Old accounts that have not been used for years are typically at risk from hackers as they may use the same passwords that have been compromised in other security breaches, which are easily available on the dark web. Any account at risk of deletion will receive “multiple notifications” before any action is taken, Google said, including to any associated recovery email addresses. The tech giant has already begun sending emails to those affected, telling users it is “to protect your private information and prevent any unauthorised access to your account even if you’re no longer using our services”. Losing access to a Gmail account could also potentially prevent people from using other online platforms and services that are associated with that email address, even if they are not related to Google. In order to keep an account active and avoid being deleted, Google users are advised to open or send an email, use Google Drive, download an app on the Google Play Store, or simply make a Google Search while logged in to the account. Any account that has posted a video to YouTube will also not be impacted, regardless of when it was last active. Read More ‘Is AI dangerous?’ UK’s most Googled questions about artificial intelligence Big tech poses ‘existential threat’ to UK journalism, survey of editors finds Political ads on Instagram and Facebook can be deepfakes, Meta says

Cybersecurity company Check Point Software Technologies Ltd. signed a deal to acquire Perimeter 81 for $490 million in

BlackBerry said on Wednesday it would separate its Internet of Things (IoT) and cybersecurity business units into two

TikTok prankster Mizzy has been arrested on suspicion of perverting the course of justice, a court has heard. The star, real name Bacari-Bronze O’Garro, appeared at Stratford Magistrates’ Court in east London on Thursday morning after he was accused of posting videos on social media without the consent of the people featured in them. He was due to stand trial on four counts of breaching a criminal behaviour order but his defence lawyer Paul Lennon applied to adjourn the hearing after telling the court that O’Garro had been arrested on October 16 on suspicion of perverting the course of justice. O’Garro’s main witness in the case, who was due to give evidence on Thursday, was also arrested and both were released on bail under the condition that they do not contact each other “directly or indirectly”, Mr Lennon explained. Without his evidence, Mr Lennon said, O’Garro would not be able to have a “fair trial”. He told the court: “It was hoped that the sole witness in his (O’Garro) favour would be able to attend court to provide evidence in support of the defence. “That is no longer possible. “Last week Mr O’Garro and his first and only witness were arrest on suspicion of perverting the course of justice. “Both were released on bail with the condition not to contact each other directly or indirectly. “Had he (the witness) not been arrested on a very serious allegation he would have been here to give evidence on behalf of Mr O’Garro. “It was hoped as of yesterday that the matter would not be proceeded with. “Instead, he (O’Garro) was bailed until January 2024.” Judge Matthew Bone rejected the defence’s submission and chose to proceed with the trial, telling the court: “The witness’s unavailability was known on or before October 16. “I am not prepared to adjourn this case. “The trial will proceed today.” O’Garro’s case was previously adjourned at the same court as he was accused of engaging in further “criminal activities”, according to a joint submission by prosecution and defence lawyers at a hearing in September. The trial will proceed later on Thursday.