AI can help generate synthetic viruses and spark pandemics, warns former Google executive
Synthetic viruses could be generated through the misuse of artificial intelligence and potentially spark pandemics, a former Google executive and AI expert has warned. Google DeepMind co-founder Mustafa Suleyman expressed concern that the use of AI to engineer pathogens to cause more harm may lead to a scenario like a pandemic. “The darkest scenario is that people will experiment with pathogens, engineered synthetic pathogens that might end up accidentally or intentionally being more transmissible or more lethal,” he said in a recent episode of a podcast. Similar to how there are restrictions in place to prevent people from easily accessing pathogenic microbes like anthrax, Mr Suleyman has called for the means to restrict access to advanced AI technology and software that runs such models. “That’s where we need containment. We have to limit access to the tools and the know-how to carry out that kind of experimentation,” he said in The Diary of a CEO podcast. “We can’t let just anyone have access to them. We need to limit who can use the AI software, the cloud systems, and even some of the biological material,” the Google DeepMind co-founder said. “And of course on the biology side it means restricting access to some of the substances,” he said, adding that AI development needs to be approached with a “precautionary principle”. Mr Suleyman’s statements echo concerns raised in a recent study that even undergraduates with no relevant background in biology can detail suggestions for bio-weapons from AI systems. Researchers, including those from the Massachusetts Institute of Technology, found chatbots can suggest “four potential pandemic pathogens” within an hour and explain how they can be generated from synthetic DNA. The research found chatbots also “supplied the names of DNA synthesis companies unlikely to screen orders, identified detailed protocols and how to troubleshoot them, and recommended that anyone lacking the skills to perform reverse genetics engage a core facility or contract research organization”. Such large language models (LLMs), like ChatGPT, “will make pandemic-class agents widely accessible as soon as they are credibly identified, even to people with little or no laboratory training,” the study said. The study, whose authors included MIT bio risk expert Kevin Esvelt, called for “non-proliferation measures”. Such measures could include “pre-release evaluations of LLMs by third parties, curating training datasets to remove harmful concepts, and verifiably screening all DNA generated by synthesis providers or used by contract research organizations and robotic ‘cloud laboratories’ to engineer organisms or viruses”. Read More China’s ‘government-approved’ AI chatbot says Taiwan invasion is likely Government urged to address AI ‘risks’ to avoid ‘spooking’ public Scientists give verdict on Harvard professor’s claim of finding materials in sea from outside Solar System Google boss says he wants to make people ‘shrug’ Why is Elon Musk obsessed with the letter X? Elon Musk ‘borrowed $1bn from SpaceX’ at same time as Twitter acquisition
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'Sophisticated' prosthetic hand found on medieval skeleton
If you thought prosthetic hands were too advanced for people living hundreds of years ago, think again. Archaeologists have found the remains of a man who died in Medieval Germany, who had prosthetics in place of several fingers. The grave was found by pipeline workers in Freising, a town near Munich. The Bavarian State Office for Monument Preservation said: “Even for experienced archaeologists, this was a particularly special find: a skeleton in which parts of the fingers of its left hand are missing.” The archaeologists removed the metal from the man’s skeleton to restore and analyse it. They came to the conclusion that he had lost his fingers at some point in his life. Walter Irlinger, deputy of the general conservator at BSOMP, said: “The hollow prosthetic on the left hand replaced four fingers. The index, middle, ring and pinky fingers are individually formed out of sheet metal and are immobile. The prosthetic fingers lie slightly curved, parallel to one another.” The prosthetic also had scraps of fabric and leather, suggesting that the fingers had a leather cover, and were tied to the hand using straps. There was also a gauze-like material inside the fingers, which may have acted as a cushion for the man’s skin from contact with the metal. That period of German history included the Thirty Years’ War, which ended in 1648, which would have increased the need for amputations and prosthetics. One of the most famous amputees from the time was Götz von Berlichingen – or “Götz of the Iron Hand”. He was a German knight who lost his right hand from a cannon injury at the siege of Landshut in 1504. “In the past, prosthetics looked very much like what they were replacing,” said Jacky Finch, a researcher in the KNH Center for Biomedical Egyptology at the University of Manchester. “Nowadays, implants are placed in the sensory system to control nerve action, rather than devices attached to the body by straps or artificially powered.” The BSOMP statement continued: “Doctors at that time were already thinking about how they could make life easier for amputees. “In central Europe, there are currently around 50 similar prostheses from the late middle ages to early modern age that are known.” How to join the indy100's free WhatsApp channel Sign up to our free indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.
2023-11-08 01:55
A crispy roast potatoes recipe could be the key to life on Earth
A chemical reaction that gives food flavour could have helped evolution, one study suggests. According to New Scientist, the Maillard reaction is when the temperature between sugars and amino acids rises above approximately 140°C. It often occurs in food such as toasted bread, meats and roasted vegetables. Caroline Peacock at the University of Leeds wanted to explore whether it could happen at lower temperatures. To do this, scientists added iron or manganese minerals to a solution made up of sugar glucose and the amino acid glycine. When the substance was incubated at 10°C, the process was sped up by around 100 times. The temperature is said to be similar to the seabed at the edges of continents. Peacock and the team discovered that the Maillard reaction also occurs on the ocean floor, where iron and manganese minerals are often found. If this is the case, it could cause the carbon in sugars and amino acids to be stored in "large, complex polymers that microbes find harder to ingest," Peacock said, as per the publication. Sign up for our free Indy100 weekly newsletter "If you can get your carbon through the 1-metre danger zone [at the top of the sea floor], where carbon generally is attacked and degraded and turned back into carbon dioxide by microbes, that will lock it away from the atmosphere," she explained. The team estimated that the minerals could lock away roughly 4 million tonnes of carbon every year. If this process didn't exist, the atmosphere could have warmed by a further 5°C over the past 400 million years, the study suggested. "This process has such a profound impact on atmospheric oxygen," she says. "Because complex life forms require higher levels of oxygen, as they’re more energetically demanding, we think it’s reasonable to surmise this process had a hand in creating conditions required for complex life." Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.
2023-08-05 00:28
US anti-affirmative action group challenges West Point admissions policy
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